Title: Cell Swelling Increases the Severity of Spreading Depression in Locusta Migratoria. 2

نویسندگان

  • Kristin E. Spong
  • Brittany Chin
  • Kelsey L. M. Witiuk
چکیده

To be considered for inclusion in the Call for Manuscripts: Comparative Approaches in Neurobiology 1 Title: Cell swelling increases the severity of spreading depression in Locusta migratoria. 2 Authors: Kristin E. Spong, Brittany Chin, Kelsey L. M. Witiuk, and R. Meldrum Robertson 3 Affiliation: Department of Biology, Queen’s University, Kingston, Ontario, Canada K7L 3N6 4 Running head: Cell swelling and spreading depression 5 Corresponding author: Kristin E. Spong 6 Contact information: 7 Email: [email protected] 8 Phone: (613)-533-6000 ext. 75510 or 77599 9 Postal address (present address): 10 Queen’s University, Department of Biology 11 Bioscience complex, Room 3404 12 Kingston, Ontario, Canada K7L 3N6 13 14 15 16 17 18 Articles in PresS. J Neurophysiol (September 16, 2015). doi:10.1152/jn.00804.2015

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منابع مشابه

CALL FOR PAPERS Comparative Approaches in Neurobiology Cell swelling increases the severity of spreading depression in Locusta migratoria

Spong KE, Chin B, Witiuk KL, Robertson RM. Cell swelling increases the severity of spreading depression in Locusta migratoria. J Neurophysiol 114: 3111–3120, 2015. First published September 16, 2015; doi:10.1152/jn.00804.2015.—Progressive accumulation of extracellular potassium ions can trigger propagating waves of spreading depression (SD), which are associated with dramatic increases in extra...

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Cell swelling increases the severity of spreading depression in Locusta migratoria.

Progressive accumulation of extracellular potassium ions can trigger propagating waves of spreading depression (SD), which are associated with dramatic increases in extracellular potassium levels ([K(+)]o) and arrest in neural activity. In the central nervous system the restricted nature of the extracellular compartment creates an environment that is vulnerable to disturbances in ionic homeosta...

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Spreading depolarization (SD) is generated in the central nervous systems of both vertebrates and invertebrates. SD manifests as a propagating wave of electrical depression caused by a massive redistribution of ions. Mammalian SD underlies a continuum of human pathologies from migraine to stroke damage, whereas insect SD is associated with environmental stress-induced neural shutdown. The gener...

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تاریخ انتشار 2015